X-RAY STRUCTURE OF TRANS-(2,5)-BIS(METHOXYMETHYL)PYRROLIDINO CARBOHYDROXAMIC ACID

The structure of the title compound has been established by X-ray diff raction analysis. C9H18N2O4, M(r) = 218.25, monoclinic, P2(1)/c a = 9. 249(5), b = 10.138(2), c = 12.175(6)Angstrom, beta = 92.21(5)degrees, V = 1141(1)Angstrom(3); Z = 4, D-x = 1.27 g.cm(-3), CuK alpha, radiati on (lambda = 1.54178 Angstrom). The final R index is 0.056 for 1860 ob served reflections. The data confirm the irans relationship between th e two methoxymethyl groups. Large deformation from the synperiplanar c onformation and a very long C-N bond are observed in the hydroxamic gr oup. An intramolecular hydrogen bond occurs between the NH and an ethe r oxygen. Molecules farm dimers by doing intermolecular H-bonds betwee n the carbonyl and the hydroxyl of the hydroxamic acid.