Presented are 10 fibroadenomas which had enlarged or were newly appear
ing in screening mammography attendees. The 10 women were aged from 42
years to 55 years, 5 being premenopausal and 5 postmenopausal, and th
ey represented 0.012% of a population attending for second or subseque
nt screening examinations. On imaging features of the lesions were ben
ign and typical of fibroadenoma. The size increases ranged from 3 mm t
o 25 mm. While the enlargement or new appearance of a solid mass lesio
n in women of this age is suspicious of malignancy, the diagnosis of f
ibroadenoma must also be considered. Recognition of the effect of horm
one replacement therapy, and careful, integrated use of imaging, clini
cal examination, cytology and core biopsy can establish a non-operativ
e diagnosis, and surgical biopsy for benign disease may be avoided.