POLYMORPHONUCLEAR LEUKOCYTES PRESENT LAMININ PEPTIDES IN ENDOCYTIC COMPARTMENTS

Authors
VANNIERSANTOS MA DESOUZA SJ BRENTANI RR DESOUZA W
Citation
Ma. Vanniersantos et al., POLYMORPHONUCLEAR LEUKOCYTES PRESENT LAMININ PEPTIDES IN ENDOCYTIC COMPARTMENTS, Biochemical and biophysical research communications, 221(3), 1996, pp. 837-842
Citations number
39
Categorie Soggetti
Biology,Biophysics
Journal title
Biochemical and biophysical research communications → ACNP
ISSN journal
0006291X
Volume
221
Issue
3
Year of publication
1996
Pages
837 - 842
Database
ISI
SICI code
0006-291X(1996)221:3<837:PLPLPI>2.0.ZU;2-3
Abstract
Rat and Human neutrophils presented cytoplasmic vacuoles immunoreactiv e for laminin at the electron microscopy level. Colocalization of the anti-laminin labeling with albumin-gold complexes and alkaline phospha tase activity in rat PMN suggest an endocytic nature for this compartm ent. Immunoblot analysis of human normal peripheral blood neutrophils revealed the presence of two laminin peptides around 100 kDa. (C) 1996 Academic Press, Inc.