Lc. Rutledge et al., EVALUATION OF THE LABORATORY RABBIT MODEL FOR SCREENING TOPICAL MOSQUITO REPELLENTS, Journal of the American Mosquito Control Association, 12(1), 1996, pp. 142-143
The laboratory rabbit was evaluated as a model for screening topical m
osquito repellents, using data obtained in tests of deet (N, N-diethyl
-3-methylbenzamide) against Aedes aegypti on humans and rabbits. Host-
specific differences in the action of the test material were quantifie
d by multiple regression analysis. The test material was less effectiv
e but more persistent in tests on rabbits, and responses of the mosqui
to test population were more variable.