Many research workers, to save time, rely entirely on either on-line o
r Off-line databases offered by an increasing number of information se
rvices. The characteristics of eight databases, including five on-line
services, were analysed in the present study concerning the retrieval
of information on dengue, the most important mosquito-borne viral dis
ease of humans. Differences in the rate of retrieval among databases w
ere apparent, depending on the main subject of publication as well as
on the geographical location of the publisher. While rates of retrieva
l of references in molecular biology were generally satisfactory (most
ly >70%), those in clinical medicine and epidemiology were not (<50%).
The latter, as published in many dengue-endemic tropical countries, w
ere found to be inadequately covered. For the global surveillance of d
engue, which has increased in intensity and spread to many countries b
ecause of increased international travel, the development of a new dat
abase emphasizing tropical geographic medicine is highly desirable.