I. Alatli et al., ORTHODONTICALLY INDUCED ROOT RESORPTION IN RAT MOLARS AFTER 1-HYDROXYETHYLIDENE-1,1-BISPHOSPHONATE INJECTION, Acta Odontologica Scandinavica, 54(2), 1996, pp. 102-108
single injection of 1-hydroxyethylidene-1,1-bisphosphonate inhibits th
e formation of acellular cementum in rat molars. Instead, an atypical
hyperplastic cementum is formed. In this study the resistance of this
cementum to resorption was tested by applying an orthodontic force. It
was found that roots lacking acellular cementum were readily resorbed
. The readiness with which the atypical hyperplastic cementum was reso
rbed without any increase in multinucleated osteoblasts may offer usef
ul opportunities to study the different phases of hard-tissue resorpti
on.