Sy. Chen et al., SYNTHESIS OF TRIMETHYLAMINE-[C-14]CARBOXYBORANE AND TRIMETHYLAMINE-[C-14]CARBOXYMETHOXYBORANE AND L1210 LEUKEMIA-CELL UPTAKE, Applied organometallic chemistry, 10(3-4), 1996, pp. 279-282
The anti-neoplastic agents trimethylamine-carboxyborane and its corres
ponding methyl ester have successfully been radiolabeled with carbon-1
4 in the carboxyl group. Using the radiolabeled agents we have shown t
hat their L1210 leukemia cell uptake appeared to be by a passive proce
ss and binding of the agents to DNA, RNA and protein over 24 h was min
imal.