Transmyocardial revascularization (TMR) is a puncture technique propos
ed as a solution for patients with coronary artery disease who cannot
be efficiently treated with the standard revascularization procedures
such as bypass surgery or percutaneous transluminal coronary angioplas
ty (PTCA). The studies presented in this review have investigated the
use of lasers to revascularize ischaemic myocardium. Needle puncture m
ethods are also briefly described. The results from experimental studi
es are not conclusive but the encouraging clinical reports raise furth
er questions about the mechanism of angina relief.