Introduction. A 69-year-old man with an uneventful past history consul
ted for a proximal subungueal leukonychia and associated paronychia of
the right greater toe. Macroscopic examination and culture lead to th
e diagnosis of Fusarium oxysporum. Local treatment with bifonazol and
cyclopirox was effective. Discussion. Fungal onychomycoses are uncommo
n and usually present as superficial leukonychia. The association of a
proximal localization with paronychia would suggest possible Fusarium
infection. Though no specific treatment protocol is well-established,
this case emphasizes the importance of effective treatment since inva
sive fusariosis is described in immunosuppressed patients with ungueal
localizations can be an important portal for infection.