M. Bogusz et al., COMPARABILITY OF RP-HPLC RETENTION INDEXES OF DRUGS IN 3 DATABASES, Journal of liquid chromatography & related technologies, 19(8), 1996, pp. 1291-1316
Citations number
33
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Three databases of HPLC retention indices in the 1-nitroalkane scale w
ere recently established (IFM = Institute of Forensic Medicine, MCL =
Microchemistry Laboratory, MTSS = Merck Tox Screening System). In two
of them (IFM and MTSS) virtually identical chromatographic conditions
were applied but different RP-columns. In the third system (MCL) a dif
ferent column and different elution conditions were used. Among a tota
l of 1149 drugs examined in all three labs, 258 drugs were common for
LFM and MTSS, 179 were common for MCL and MTSS, 162 were common for IF
M and MCL, and 135 drugs were common for all three databases.