IDENTIFICATION OF FREE STEROLS IN CEREBRAL WHITE-MATTER OF RATS UPON OXYGEN DEFICIENCY USING GAS-CHROMATOGRAPHY MASS-SPECTROMETRY

Authors
PLAZIAK AS ADAMCZEWSKAGONCERZEWICZ Z DORSZEWSKA J
Citation
As. Plaziak et al., IDENTIFICATION OF FREE STEROLS IN CEREBRAL WHITE-MATTER OF RATS UPON OXYGEN DEFICIENCY USING GAS-CHROMATOGRAPHY MASS-SPECTROMETRY, Polish Journal of Chemistry, 70(5), 1996, pp. 578-588
Citations number
35
Categorie Soggetti
Chemistry
Journal title
Polish Journal of Chemistry → ACNP
ISSN journal
01375083
Volume
70
Issue
5
Year of publication
1996
Pages
578 - 588
Database
ISI
SICI code
0137-5083(1996)70:5<578:IOFSIC>2.0.ZU;2-8
Abstract
The total lipid fraction has been extracted from the white matter of f emale rats upon acute and moderate hypoxia. Using GC-MS to analyse the extracts, a number of hydrocarbon compounds (mainly aliphatic) and fr ee sterols were identified. Cholesterol, desmosterol, 24-ethylcholeste rol, 24-ethyl-4-cholesten-3-on and 22-propyl-3 beta-hydroxy-5,24-chole stadien were identified either by GC-MS analysis of standards, or by i nterpretation of their mass spectra. Other steroid compounds, due to t heir extremely low concentrations in extracts, were not identified.