LEAD-PROMOTED 2-CARBOETHOXYALLYLATION OR 2-CARBOXYLALLYLATION OF ALDEHYDES - A NEW AND FACILE METHOD FOR THE SYNTHESIS OF ALPHA-METHYLENE-GAMMA-BUTYROLACTONES

Authors
ZHOU JY JIA Y YAO XB WU SH
Citation
Jy. Zhou et al., LEAD-PROMOTED 2-CARBOETHOXYALLYLATION OR 2-CARBOXYLALLYLATION OF ALDEHYDES - A NEW AND FACILE METHOD FOR THE SYNTHESIS OF ALPHA-METHYLENE-GAMMA-BUTYROLACTONES, Synthetic communications, 26(12), 1996, pp. 2397-2406
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
26
Issue
12
Year of publication
1996
Pages
2397 - 2406
Database
ISI
SICI code
0039-7911(1996)26:12<2397:L2O2OA>2.0.ZU;2-U
Abstract
In the presence of powdered lead, the reaction of aldehydes and alpha- bromomethylacrylate (or alpha-bromomethylacrylic acid) can be carried out under mild condition, the products 4-hydroxy-2-methylenebutanoates (or 4-hydroxy-2-methylenebutanoic acids) can be easily converted to a lpha- methylene-gamma-butyrolactones in the presence of CF3COOH.