Amsc. Demelo et al., NISIN STIMULATES OXYGEN-CONSUMPTION BY STAPHYLOCOCCUS-AUREUS AND ESCHERICHIA-COLI, Applied and environmental microbiology, 62(5), 1996, pp. 1831-1834
Nisin stimulated oxygen consumption by nongrowing, glucose-metabolizin
g Staphylococcus aureus and Escherichia coil cells, indicating a proto
nophore mode of action. A similar stimulation in E. coil cells osmotic
ally stressed to disrupt the outer cell membrane confirmed the cytopla
smic membrane as the site of nisin action and showed that nisin uptake
was not prevented by the outer membrane.