CLINICAL MANIFESTATIONS OF HIV-INFECTION AND ITS CLASSIFICATION ASPECTS

The clinical manifestations and some immunological parameters (CD4 lym phocytes, CD4/CD8 ratio, IgM, IgA, IgG levels, skin-test) were examine d in 226 adult patients (148 males and 78 females) infected with HIV. These included 58 (26 %) asymptomatic patients with seropositive test, 109 (48 %) with the only clinical manifestation generalized lymphaden opathy; 54 (24 %) with AIDS-related infections, 5 (2%) with AIDS. A su bsequent follow-up of 3 months to 3 years demonstrated that AIDS devel oped in 7 patients, 9 died. The period of infection with HIV and death ranged from 1.5 to 9 years. The signs of cell immunodeficiency were f ound in 70 % of the examinees. Recommendations are given on the classi fication of HIV infection.