AN IMPROVED SYNTHESIS OF 8-BROMO-2'-DEOXYGUANOSINE

Authors
GANNETT PM SURA TP
Citation
Pm. Gannett et Tp. Sura, AN IMPROVED SYNTHESIS OF 8-BROMO-2'-DEOXYGUANOSINE, Synthetic communications, 23(11), 1993, pp. 1611-1615
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
23
Issue
11
Year of publication
1993
Pages
1611 - 1615
Database
ISI
SICI code
0039-7911(1993)23:11<1611:AISO8>2.0.ZU;2-6
Abstract
A new synthesis of 8-bromo-2-deoxyguanosine, a key intermediate in the synthesis of the mutagenic DNA adduct 8-oxo-2'-deoxyguanosine is desc ribed. The advantages of this method are significantly improved yields and ease of isolation.