TREATMENT OF STAPHYLOCOCCUS-AUREUS CATHETER-RELATED INFECTION AND INFECTIVE ENDOCARDITIS WITH GRANULOCYTE-COLONY-STIMULATING FACTOR IN THE EXPERIMENTAL RABBIT MODEL
U. Frank et Hf. Chambers, TREATMENT OF STAPHYLOCOCCUS-AUREUS CATHETER-RELATED INFECTION AND INFECTIVE ENDOCARDITIS WITH GRANULOCYTE-COLONY-STIMULATING FACTOR IN THE EXPERIMENTAL RABBIT MODEL, Antimicrobial agents and chemotherapy, 40(5), 1996, pp. 1308-1310
The role of granulocyte colony-stimulating factor with and without ant
ibiotics in the treatment of catheter-related infection and infective
endocarditis caused by methicillin-susceptible Staphylococcus aureus w
as assessed in the experimental rabbit model. Granulocyte colony-stimu
lating factor stimulated leukocytosis in infected animals but did not
increase the clearance of methicillin-susceptible S. aureus from perip
heral blood, subcutaneous port catheters, intravascular cardiac cathet
ers, or aortic valve vegetations.