COMPUTER-AIDED DATA-ACQUISITION AND ANALYSIS OF ACETLYCHOLINESTERASE VELOCITY SEDIMENTATION PROFILES

Authors
RIBARIC S PETEREC D SKETELJ J
Citation
S. Ribaric et al., COMPUTER-AIDED DATA-ACQUISITION AND ANALYSIS OF ACETLYCHOLINESTERASE VELOCITY SEDIMENTATION PROFILES, Computer methods and programs in biomedicine, 49(2), 1996, pp. 149-156
Citations number
10
Categorie Soggetti
Mathematical Methods, Biology & Medicine","Computer Science Interdisciplinary Applications","Engineering, Biomedical","Computer Science Theory & Methods","Medical Informatics
Journal title
Computer methods and programs in biomedicine → ACNP
ISSN journal
01692607
Volume
49
Issue
2
Year of publication
1996
Pages
149 - 156
Database
ISI
SICI code
0169-2607(1996)49:2<149:CDAAOA>2.0.ZU;2-O
Abstract
Acetylcholinesterase (AChE) is an enzyme that appears in several molec ular forms. Individual AChE molecular forms can be isolated and identi fied on the basis of their velocity sedimentation profiles. We have im proved an existing method for analyzing AChE sedimentation profiles wi th a computer aided data acquisition and analysis system. The software facilitates measurements of AChE activity of individual molecular for ms and comparison among AChE velocity sedimentation profiles. In pract ice, our program increased precision and reduced the time of AChE velo city sedimentation profile analysis. The software can also be applied to velocity sedimentation analysis of other proteins. We plan to upgra de the program by making it compatible with Microsoft Windows.