NONCONVENTIONAL AGENTS FOR OPTICAL RESOLUTIONS

Authors
FOGASSY E KOZMA D
Citation
E. Fogassy et D. Kozma, NONCONVENTIONAL AGENTS FOR OPTICAL RESOLUTIONS, Molecular crystals and liquid crystals science and technology. Section A, Molecular crystals and liquid crystals, 276, 1996, pp. 37-45
Citations number
21
Categorie Soggetti
Crystallography
Journal title
Molecular crystals and liquid crystals science and technology. Section A, Molecular crystals and liquid crystals → ACNP
ISSN journal
1058725X
Volume
276
Year of publication
1996
Pages
37 - 45
Database
ISI
SICI code
1058-725X(1996)276:<37:NAFOR>2.0.ZU;2-S
Abstract
In this paper we demonstrate the use of chiral drugs and intermediates as resolving agents on 13 examples from our practice. In 11 cases of 13, the configuration of the enantiomers in the precipitated salt is o pposite, which support the assumption that the formation of a ''quasi racemate'' type diastereoisomeric salt may be preffered, when the race mate and the resolving agent are structurally similar or at least ther e is no significant difference between their molecular weight.