The high incidence of abortion in Brazil and the increased use of miso
prostol among women having clandestine/unsafe abortions has led to an
interest in evaluating whether there is an association between the use
of misoprostol and the incidence of septic complications post-abortio
n. To test this association, a retrospective cohort study was conducte
d with 1840 women treated post-abortion at the Institute Materno-Infan
til de Pernambuco (IMIP) between 1988 and 1992. Incidence of infection
(4.2%) was lower in women stating they had used misoprostol than in t
hose stating that the abortion was not induced (7.9%) and twelve times
lower than in women stating that they had used other methods (49.4%).
These results suggest that misoprostol is a safe, inexpensive method
for inducing abortion, and leads to fewer complications and consequent
ly shorter hospital stays. Misoprostol should be considered a viable o
ption in situations where induction of abortion is legal or medically
indicated.