BLOOD-GLUCOSE LEVELS IN HYPERTENSIVE PATIENTS DURING TREATMENT WITH DIFFERENT ANTIHYPERTENSIVE AGENTS

Fasting blood glucose was determined in 27 adults with essential hyper tension at four different periods during a 12-month treatment with dox azosin, an alpha-adrenoceptor antagonist, and in another set of 20 adu lt hypertensive patients, after 3 months treatment with amlodipine, a calcium antagonist. The mean fasting blood glucose levels at various d eterminations during doxazosin therapy did not show any significant va riation from the pre-treatment value. Similarly, mean fasting blood gl ucose level remained the same after 3 months of amlodipine therapy. Th e findings, therefore, highlights the safety of doxazosin and amlodipi ne antihypertensive pharmacotherapies.