THE ROLE OF INSULIN-LIKE GROWTH-FACTOR IN SENESCENCE - CLUES FOR INTERVENTIONAL STRATEGIES IN THE ELDERLY

Citation
Cj. Rosen et Cr. Kessenich, THE ROLE OF INSULIN-LIKE GROWTH-FACTOR IN SENESCENCE - CLUES FOR INTERVENTIONAL STRATEGIES IN THE ELDERLY, The Endocrinologist, 6(2), 1996, pp. 102-108
Citations number
37
Categorie Soggetti
Endocrynology & Metabolism
Journal title
ISSN journal
10512144
Volume
6
Issue
2
Year of publication
1996
Pages
102 - 108
Database
ISI
SICI code
1051-2144(1996)6:2<102:TROIGI>2.0.ZU;2-9
Abstract
The fastest growing segment of our population is the elderly. By the t urn of the century, 13% of the population in the United States will be more than 65 years of age. A prime goal of geriatric medicine is to c ompress the morbidities of aging into as small a period as possible at the extreme end of life. It has been postulated that restoration of a ''growth hormone axis'' more akin to that which exists in youth may p lay an important role in this effort. We review the data, pro and con, that bear on this hypothesis.