NAIL MATRIX NEVI - A CLINICAL AND HISTOPATHOLOGIC STUDY OF 22 PATIENTS

Citation
A. Tosti et al., NAIL MATRIX NEVI - A CLINICAL AND HISTOPATHOLOGIC STUDY OF 22 PATIENTS, Journal of the American Academy of Dermatology, 34(5), 1996, pp. 765-771
Citations number
19
Categorie Soggetti
Dermatology & Venereal Diseases
ISSN journal
01909622
Volume
34
Issue
5
Year of publication
1996
Part
1
Pages
765 - 771
Database
ISI
SICI code
0190-9622(1996)34:5<765:NMN-AC>2.0.ZU;2-D
Abstract
Background: Because most dermatologists do not regularly perform biops ies of longitudinal melanonychia, even when the pigmentation presents as a single band, the true prevalence of nail matrix nevi is unknown. Objective: Our purpose was to determine the prevalence of nail matrix nevi in white patients with longitudinal melanonychia involving a sing le digit and to determine whether longitudinal melanonychia caused by a nail matrix nevus can be clinically distinguished from longitudinal melanonychia from other causes. Methods: From January 1989 to December 1994 we performed a nail biopsy on 100 of 128 consecutive white patie nts who had a single band of ''idiopathic'' longitudinal melanonychia. Results: A nail matrix nevus was detected in 22 patients, A junctiona l nevus was found in 19 specimens and a compound nevus in three specim ens. Conclusion: Nail matrix nevi in Caucasian patients are uncommon b ut not exceptional. The number of nevi presenting with longitudinal me lanonychia exceeded that of melanoma. The diagnosis of nail matrix nev i is impossible clinically and always requires histopathologic study. The pathologic features of nail matrix nevi are similar to those of sk in nevi except for their architectural pattern, which reflects the pec uliar anatomy of the nail unit.