DAMAGE TO PSEUDOMONAS-AERUGINOSA PAO1 BACTERIOPHAGE-F116 DNA BY BIOCIDES

Authors
MAILLARD JY BEGGS TS DAY MJ HUDSON RA RUSSELL AD
Citation
Jy. Maillard et al., DAMAGE TO PSEUDOMONAS-AERUGINOSA PAO1 BACTERIOPHAGE-F116 DNA BY BIOCIDES, Journal of Applied Bacteriology, 80(5), 1996, pp. 540-544
Citations number
20
Categorie Soggetti
Microbiology,"Biothechnology & Applied Migrobiology
Journal title
Journal of Applied Bacteriology → ACNP
ISSN journal
00218847
Volume
80
Issue
5
Year of publication
1996
Pages
540 - 544
Database
ISI
SICI code
0021-8847(1996)80:5<540:DTPPBD>2.0.ZU;2-S
Abstract
The mechanism of action of biocides against viruses has not been widel y studied, although two main targets are viral proteins (capsids, enzy mes) and the viral genome. This study was undertaken in order to inves tigate the efficacy of several disinfectants against the nucleic acid of the Pseudomonas aeruginosa PAO bacteriophage F116. Of all the bioci des tested, only peracetic acid affected significantly the phage genom e. However, it is not clear whether the nucleic acid was damaged insid e the phage capsid or when released into the surrounding medium.