UBIQUITIN EXPRESSION IN DEGENERATING AXONS OF EQUINE CERVICAL COMPRESSIVE MYELOPATHY

Authors
JORTNER BS SCARRATT WK MODRANSKY PD WALTON A PERKINS SK
Citation
Bs. Jortner et al., UBIQUITIN EXPRESSION IN DEGENERATING AXONS OF EQUINE CERVICAL COMPRESSIVE MYELOPATHY, Veterinary pathology, 33(3), 1996, pp. 356-359
Citations number
10
Categorie Soggetti
Veterinary Sciences",Pathology
Journal title
Veterinary pathology → ACNP
ISSN journal
03009858
Volume
33
Issue
3
Year of publication
1996
Pages
356 - 359
Database
ISI
SICI code
0300-9858(1996)33:3<356:UEIDAO>2.0.ZU;2-Q
Abstract
Neuropathologic examination revealed axonal swelling and breakdown lea ding to Wallerian degeneration of affected myelinated nerve fibers in the spinal cord white matter of four young horses with equine cervical compressive myelopathy. Immunohistochemical reactions for the cell st ress protein ubiquitin revealed an enhanced presence in the swollen ax ons, which may reflect a role for ubiquitin in the neuronal catabolic process of axonal compression and degeneration in this myelopathy.