REGIOSELECTIVE RIBOSYLATION OF 6,7-DICHLOROIMIDAZO[4,5-B]QUINOLIN-2-ONE

Citation
Zj. Zhu et Lb. Townsend, REGIOSELECTIVE RIBOSYLATION OF 6,7-DICHLOROIMIDAZO[4,5-B]QUINOLIN-2-ONE, Tetrahedron letters, 37(19), 1996, pp. 3263-3266
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404039
Volume
37
Issue
19
Year of publication
1996
Pages
3263 - 3266
Database
ISI
SICI code
0040-4039(1996)37:19<3263:RRO6>2.0.ZU;2-7
Abstract
Regioselective ribosylation conditions were established which gave bot h -beta-D-ribofuranosyl)imidazo[4,5-b]quinolin-2-one (4) and -beta-D-r ibofuranosyl)imidazo[4,5-b]quinolin-2-one (5), respectively, in high y ield from 6,7-dichloroimidazo[4,5-b]quinolin-2-one (6). The distributi ons of the sites of ribosylation under a variety of conditions are dis cussed. (C) 1996 Elsevier Science Ltd.