AMINO-ACID RACEMIZATION AND THE PRESERVATION OF ANCIENT DNA

Citation
Hn. Poinar et al., AMINO-ACID RACEMIZATION AND THE PRESERVATION OF ANCIENT DNA, Science, 272(5263), 1996, pp. 864-866
Citations number
39
Categorie Soggetti
Multidisciplinary Sciences
Journal title
ISSN journal
00368075
Volume
272
Issue
5263
Year of publication
1996
Pages
864 - 866
Database
ISI
SICI code
0036-8075(1996)272:5263<864:ARATPO>2.0.ZU;2-9
Abstract
The extent of racemization of aspartic acid, alanine, and leucine prov ides criteria for assessing whether ancient tissue samples contain end ogenous DNA, In samples in which the D/L ratio of aspartic acid exceed s 0.08, ancient DNA sequences could not be retrieved. Paleontological finds from which DNA sequences purportedly millions of years old have been reported show extensive racemization, and the amino acids present are mainly contaminates, An exception is the amino acids in some inse cts preserved in amber.