VITILIGO IS ASSOCIATED WITH HLA-A2 AND HLA-DW7 IN THE SLOVAK POPULATION

Authors
BUC M BUSOVA B HEGYI E KOLIBASOVA K
Citation
M. Buc et al., VITILIGO IS ASSOCIATED WITH HLA-A2 AND HLA-DW7 IN THE SLOVAK POPULATION, Folia biologica, 42(1-2), 1996, pp. 23-25
Citations number
18
Categorie Soggetti
Biology
Journal title
Folia biologica → ACNP
ISSN journal
00155500
Volume
42
Issue
1-2
Year of publication
1996
Pages
23 - 25
Database
ISI
SICI code
0015-5500(1996)42:1-2<23:VIAWHA>2.0.ZU;2-L
Abstract
By investigating a group of 67 unrelated adult persons suffering from vitiligo it was found that antigens HLA-A2 and HLA-Dw7 differed in the ir frequencies in comparison to those observed in the healthy populati on. The antigen HLA-A2 was found in 76.12% of patients compared to 43. 95% in the control group (chi(2) = 25.61, P < 0.005, RR = 4.07). The a ntigen HLA-Dw7 was present in 56.71% of patients compared to 15.8% in the healthy population (chi(2) = 26.55, P < 0.0001, RR = 6.98). No oth er significant deviations in the frequencies of investigated antigens were observed.