Infantile colic is characterized by persistent crying, diminished soot
hability, and excessive activity or restlessness. The purpose of this
study was to explore the processes underlying the persistent, recurren
t irritability by investigating behavioral and interactional differenc
es in irritable and nonirritable infants. In this two-group longitudin
al study, 40 infants and their mothers were followed over the first 4
months of life. Statistically significant differences between the two
groups were found, with the irritable infants demonstrating an increas
e in the amount and intensity of crying, more disruption in sleep-wake
states, and less synchrony in mother-infant interaction.