ENDEMIC MYCOSIS COMPLICATING HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION

Citation
Ga. Sarosi et Sf. Davies, ENDEMIC MYCOSIS COMPLICATING HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION, Western journal of medicine, 164(4), 1996, pp. 335-340
Citations number
43
Categorie Soggetti
Medicine, General & Internal
Journal title
ISSN journal
00930415
Volume
164
Issue
4
Year of publication
1996
Pages
335 - 340
Database
ISI
SICI code
0093-0415(1996)164:4<335:EMCHI>2.0.ZU;2-2
Abstract
Persons infected with the human immunodeficiency virus are prone to th e development of many fungal diseases. Normal hosts with intact immuni ty usually recover from infection by these less-invasive fungi. In per sons with compromised T-cell-mediated immunity, however, widespread di ssemination from a pulmonary focus occurs. In this review, we discuss the epidemiology, clinical manifestations, diagnosis, and treatment of the three major North American mycoses, histoplasmosis, blastomycosis , and coccidioidomycosis. In most cases, amphotericin B is the initial drug of choice, followed by one of the azoles for lifelong maintenanc e therapy.