PRIMARY SCLEROSING CHOLANGITIS AND COLITI S ULCEROSA IN CHILDREN

In one of two children suffering from a primary sclerosing cholangitis , the liver disease was clinically the main problem and only later a c olitis was diagnosed additionally. In the second case, the colitis ulc erosa was clinically dominant, and only the elevation of serum aminotr ansferase led to the diagnosis of a mild early form of primary scleros ing cholangitis. Reviewing the literature the etiological, immunologic al, diagnostical, clinical and therapeutical aspects of this disease a re described.