BEHCETS-SYNDROME WITH PULMONARY INVOLVEMENT - COMBINED THERAPY FOR ENDOBRONCHIAL STENOSIS USING NEODYM-YAG LASER, BALLOON DILATION AND IMMUNOSUPPRESSION
C. Witt et al., BEHCETS-SYNDROME WITH PULMONARY INVOLVEMENT - COMBINED THERAPY FOR ENDOBRONCHIAL STENOSIS USING NEODYM-YAG LASER, BALLOON DILATION AND IMMUNOSUPPRESSION, Respiration, 63(3), 1996, pp. 195-198
We present a case report of a patient suffering from Behcet's syndrome
with pulmonary involvement. The development of endobronchial granulom
atosis in the bronchus intermedius and right upper lobe bronchus led t
o severe bronchial stenosis and dyspnoea. Also aphthous ulcerations in
the bronchial mucosa occurred. Treatment of the granulomatous stenosi
s consisted of Neodym-YAG laser resection and immunosuppression. On fo
llow-up there was a recurrence of the stenosis, characterised by fibro
tic strictures. Therefore a balloon dilation was performed and immunos
uppression instituted, which led to an increase in airway diameter and
a reduction in dyspnoea. These clinical results suggest that recanali
sation therapy with Neodym-YAG laser and/or balloon dilation with addi
tional immunosuppression is suitable in benign stenosis (granulomatous
or fibrotic), caused by Behcet's disease.