The Ronnskar smelter in Skelleftea, Sweden, produces significant envir
onmental pollutants, such as lead, arsenic, copper, cadmium and sulphu
r dioxide. The purpose of the present study was to determine whether c
hildren born to women living near the smelter during pregnancy had an
increased risk of childhood cancer. The study group consisted of child
ren born between 1961 and 1990 in the municipality of Skelleftea and p
arish of Holmsund. Through linkage to the Swedish Cancer Registry canc
er diagnoses in the study group were obtained and compared with the ex
pected ones based on the national incidence rates, Thirteen cases of c
hildhood cancer were identified among children born in the vicinity of
the smelter against 6.7 expected (SIR 195, 95%CI 88-300), Among dista
nt born the observed number of cases (n=42) was similar to that expect
ed (n=41.8).