A NEW TC-99M LABELED PORPHYRIN FOR SPECIFIC IMAGING OF SARCOMA-120 - SYNTHESIS AND BIOLOGICAL STUDY IN A SWISS MOUSE MODEL

Authors
SHETTY SJ MURUGESAN S CHATTERJEE SR BANERJEE S SRIVASTAVA TS NORONHA OPD SAMUEL AM
Citation
Sj. Shetty et al., A NEW TC-99M LABELED PORPHYRIN FOR SPECIFIC IMAGING OF SARCOMA-120 - SYNTHESIS AND BIOLOGICAL STUDY IN A SWISS MOUSE MODEL, Journal of labelled compounds & radiopharmaceuticals, 38(5), 1996, pp. 411-418
Citations number
13
Categorie Soggetti
Chemistry Analytical","Pharmacology & Pharmacy","Biochemical Research Methods
Journal title
Journal of labelled compounds & radiopharmaceuticals → ACNP
ISSN journal
03624803
Volume
38
Issue
5
Year of publication
1996
Pages
411 - 418
Database
ISI
SICI code
0362-4803(1996)38:5<411:ANTLPF>2.0.ZU;2-S
Abstract
A new porphyrin o-5,10,15,20-tetrakis[3,4-bis(carboxymethyleneoxy- phe nyl]porphyrin (T3,4BCPP) was synthesised and efficiently labeled with Tc-99m. On injecting this Tc-99m labeled porphyrin to abdominal Sarcom a 120 bearing Swiss mice it accumulated in the abdominal tumour. This radiolabeled complex can thus be used for tumour detection and diagnos is.