I. Sekine et al., ROENTGENOGRAPHICALLY OCCULT SMALL-CELL LUNG-CANCER - CASE-REPORT AND REVIEW OF THE LITERATURE, Mayo Clinic proceedings, 71(5), 1996, pp. 481-484
This report describes a rare case of roentgenographically occult small
-cell lung cancer in a 73-year-old man with hemoptysis. Fiberoptic bro
nchoscopy disclosed a 5-mm dome-shaped lesion; a biopsy established th
e diagnosis of small-cell lung cancer. The patient received a combinat
ion of chemotherapy and radiotherapy. More than 10 years later, he is
still alive without recurrent disease. A review of the literature of r
oentgenographically occult small-cell lung cancer revealed the followi
ng: (1) a history of heavy smoking was common; (2) double primary bron
chogenic carcinoma was noted; (3) hemoptysis or bloody sputum was an i
nitial common symptom; (4) the sensitivity of sputum cytologic analysi
s was relatively low; (5) the tumor, which was shiny, smooth, and cove
red with bronchial epithelium, was often located at the bifurcation; a
nd (6) lymph node metastatic involvement occurred.