N. Samiy et al., INHALED STEROIDS - EFFECT ON INTRAOCULAR-PRESSURE IN PATIENTS WITHOUTGLAUCOMA, Canadian journal of ophthalmology, 31(3), 1996, pp. 120-123
Objective: To evaluate the risk of intraocular pressure (IOP) elevatio
n in patients receiving inhaled steroid therapy. Design: Prospective s
tudy. Setting: Four private practices in New Jersey. Patients: A total
of 187 patients (99 men and 88 women) with no documented history of g
laucoma about to begin inhaled steroid therapy for various pulmonary c
onditions were enrolled, Of the 187, 183 were followed at 12 weeks. In
terventions: Measurement of the IOP with the Tone-Pen before therapy w
as started and 12 weeks after therapy was started. Outcome measure: IO
P. Results: No significant rise in IOP was observed. No patient had a
rise in IOP greater than 4 mm Hg. Conclusions: Although isolated case
reports indicate a definite risk of glaucoma in the presence of inhale
d steroid therapy, the risk appears to be small.