POLAROGRAPHIC-REDUCTION OF SOME TRIPHENYLMETHANE DYES AND THEIR POTENTIAL CARCINOGENIC ACTIVITY

Polarographic reduction of some triphenylmethane dyes in strictly anhy drous solutions was studied in the absence and presence of alpha-lipoi c acid. The values of the half-wave potentials E(1/2) and the paramete r of potential carcinogenicity tg alpha were determined for all compou nds studied. The current value of the first diffuse polarographic wave was increased in the presence of alpha-lipoic acid for all of the com pounds. The increase was linear and depended on the alpha-lipoic acid concentration in anhydrous solutions. The highest determined value of tg alpha belonged to crystal violet (0.420) and to methyl violet 2B (0 .440). The values indicate potential carcinogenic activities of the re spective triphenylmethane dyes.