ANTENATAL INVASIVE AND NONINVASIVE MANAGEMENT OF ALLOIMMUNE THROMBOCYTOPENIA

Authors
KORNFELD I WILSON RD BALLEM P WITTMANN BK FARQUHARSON DF
Citation
I. Kornfeld et al., ANTENATAL INVASIVE AND NONINVASIVE MANAGEMENT OF ALLOIMMUNE THROMBOCYTOPENIA, Fetal diagnosis and therapy, 11(3), 1996, pp. 210-217
Citations number
46
Categorie Soggetti
Obsetric & Gynecology
Journal title
Fetal diagnosis and therapy → ACNP
ISSN journal
10153837
Volume
11
Issue
3
Year of publication
1996
Pages
210 - 217
Database
ISI
SICI code
1015-3837(1996)11:3<210:AIANMO>2.0.ZU;2-7
Abstract
The outcome analysis of 10 pregnancies at risk for neonatal alloimmune thrombocytopenia (NAIT) is presented. An experimental protocol of cor docentesis and maternal administration of intravenous immunoglobulin ( IVIG) is compared to a control group of older untreated affected sibli ngs, The outcome in pregnancies treated with IVIG shows improved fetal platelet count in 70% and no intraventricular hemorrhage, We conclude that maternal administration of IVIG appears to improve clinical outc ome in fetuses at risk for NAIT.