A comprehensive number of body composition predictions (involving weig
ht, height, skinfold thicknesses, bioelectrical impedance and near-inf
rared interactance-NIRI) were evaluated against total body water (TBW
from isotope dilution), in 23 randomly selected men over 75 years old,
and dual-energy X-ray absorptiometry (DXA), in 15 volunteers from thi
s group. Comparisons were made between anthropometric and impedance me
thods for estimating limb muscle mass (obtained using DXA). Bias and 9
5% limits of agreement between measured TBW and DXA estimates were -2.
1 kg and 3.1 kg, respectively (for fat, 5.4% and 6.1% body weight). Ag
reement between TBW predictions and reference measurements was remarka
bly variable, irrespective of whether TBW was predicted from TBW-speci
fic equations or indirectly from estimates of fat or fat-free mass: fo
r predictions using anthropometry, bias ranged from -4.7 kg to 1.6 kg
and 95% limits of agreement from bias +/- 3.8 kg to +/- 5.0 kg; using
impedance, bias was -8.8 kg to 3.2 kg and 95% limits of agreement were
bias +/- 3.6 kg to +/- 7.8 kg; corresponding values for NIRI were -5.
3 kg and +/- 5.4 kg. Although some non-age-specific equations appeared
valid, age-specific equations generally predicted TBW better. Limb mu
scle mass (DXA) was predicted better using the segmental impedance met
hod, from indices of limb muscle area (r = 0.76; SEE = 1.9 kg) and vol
ume (r = 0.86; SEE = 1.6 kg), than by anthropometry alone (r = 0.61 an
d 0.71; SEE = 2.3 kg and 2.1 kg, respectively). In conclusion, some bo
dy composition predictions are unacceptable (at least for TBW) in olde
r men, and care is recommended when selecting from these methods or eq
uations. Also, the segmental impedance method is as good as, if not be
tter than, anthropometry alone in predicting limb muscle mass (DXA) in
older men.