OCCURRENCE OF IMMUNOREACTIVE ACTIVIN INHIBIN BETA(B) IN GONADOTROPHS,THYROTROPHS, AND SOMATOTROPHS OF THE XENOPUS PITUITARY/

Authors
UCHIYAMA H KOMAZAKI S ASASHIMA M KIKUYAMA S
Citation
H. Uchiyama et al., OCCURRENCE OF IMMUNOREACTIVE ACTIVIN INHIBIN BETA(B) IN GONADOTROPHS,THYROTROPHS, AND SOMATOTROPHS OF THE XENOPUS PITUITARY/, General and comparative endocrinology, 102(1), 1996, pp. 1-10
Citations number
42
Categorie Soggetti
Endocrynology & Metabolism
Journal title
General and comparative endocrinology → ACNP
ISSN journal
00166480
Volume
102
Issue
1
Year of publication
1996
Pages
1 - 10
Database
ISI
SICI code
0016-6480(1996)102:1<1:OOIAIB>2.0.ZU;2-9
Abstract
An antibody against the Xenopus activin/inhibin beta(B) subunit (94-10 7) was raised in a rabbit. Using this antibody, the distribution of ac tivin/inhibin beta(B) immunoreactivity in the pituitary of adult X. la evis was studied. beta(B) immunoreactivity was detected in gonadotroph s, thyrotrophs, and somatotrophs under light microscopy. Electron micr oscopy revealed that a beta(B)-immunoreactive substance exists in LH, TSH, and GH granules, in contrast to findings in the rat and goldfish. These results indicate that the expression of activin/inhibin beta(B) in pituitary cells is not consistent among vertebrate species. (C) 19 96 Academic Press, Inc.