BRONCHIOLITIS OBLITERANS ORGANIZING PNEUMONIA ASSOCIATED WITH SYSTEMIC LUPUS-ERYTHEMATOSUS WITH ANTIPHOSPHOLIPID ANTIBODY

Bronchiolitis obliterans organizing pneumonia (BOOP) is a pathologic e ntity characterized by the formation of fibrous tissue plugs within te rminal bronchioles and alveolar ducts. Although BOOP has been associat ed with several connective tissue disorders, there are rare reports of BOOP in patients with systemic lupus erythematosus (SLE). We present a patient with SLE accompanying antiphospholipid antibody who develope d recurrent respiratory symptoms and radiographic abnormalities. The d iagnosis of BOOP was confirmed by transbronchial lung biopsy. This cas e suggests that not only SLE, but also the presence of antiphospholipi d antibody, may be associated with the development of BOOP.