DIFFERENTIAL CHARACTERISTICS OF THE TEMPE RATURE-SENSITIVE PERIOD OF THE LAWC(P1) MUTATION ON THE BASIS OF MACROCHAETAE OVEREXPRESSION IN DROSOPHILA

Temperature-sensitive periods (TSPs) of lawc(p1) mutations were studie d via the frequencies of arising of extras macrochaetae for each macro chaeta type separately. TSPs for the formation of extras macrochaetae of original classes were unevenly distributed within larval instars It and m. It was found that macrochaetae of different types differed fro m one another in their temperature sensitivity. The TSP of development of macrochaetae belonging to new ectopic classes was multiphase, with the first phase at larval instar II, and the second phase, at the pre pupal to early pupal stage. It is assumed that in Drosophila, the prod ucts of the lawc gene participate, along with other genes, in the deve lopment of the nervous system through regulation of ac-sc expression, both in proneural clusters and outside them.