PROTEIN-LOSING GASTROPATHY ASSOCIATED WITH CYTOMEGALOVIRUS - A RARE AND LATE COMPLICATION OF ALLOGENEIC BONE-MARROW TRANSPLANTATION

A 36-year-old woman with chronic myelogenous leukemia in first chronic phase received a bone marrow transplant from her HLA-identical brothe r. The preparatory regimen consisted of total body irradiation (10 Gy) and cyclophosphamide (60 mg/kg for 2 days), Full engraftment was achi eved and the woman was monitored as an outpatient after discharge from hospital on day 35, One year after BMT, while she was on cyclosporin A and steroids because of chronic graft-versus-host disease, the patie nt developed protein-losing gastropathy associated with cytomegaloviru s infection (with no gastrointestinal symptoms), which regressed spont aneously in 4 weeks.