The aim of the present study was to clarify, by means of transcranial
colour-coded duplex sonography of the basilar artery, whether there ar
e changes in basilar artery blood flow in patients with acute inner ea
r disturbances and whether the flow in the basilar artery is affected
by acoustic stimuli in such patients and in normal, healthy controls.
Method: Basilar artery blood flow velocity was measured in 52 patients
with severe inner ear impairment over a period of tow weeks by means
of conventional transcranial Doppler sonography and transcranial colou
r-coded duplex sonography. The same measurements were carried out in 4
5 healthy control subjects. At the end of the two week period, both pa
tients and controls were exposed to 70-dB noise, with basilar artery f
low evaluated before and during exposure. The basilar artery Doppler c
urves were analysed for systolic flow velocity, end-diastolic flow vel
ocity, resistance index (Pourcelot) and pulsatility index (Gosling). R
esults: During the first two days of the study, the basilar artery res
istance index and pulsatility index were significantly (p < 0.001) hig
her in patients than in controls. During noise exposure, both patients
and controls showed significant (p < 0.01) increases in these indices
. Conclusion: This study shows that temporary increases in the basilar
artery resistance index and pulsatility index are found both in the a
cute phase of inner ear disease and during exposure to noise.