RENAL-CELL CARCINOMA IN ASSOCIATION WITH TUBEROUS SCLEROSIS IN CHILDREN

Tuberous sclerosis, a genetically transmitted multisystem tem neurocut aneous disorder, is associated with renal lesions in 50% of cases. The expected lesions are angiomyolipomas or renal cysts; renal cell carci noma has been encountered in adults who have tuberous sclerosis. but i s very rare in children. The authors report the case of a 5 year-old g irl with tuberous sclerosis for whom atypical computed tomography find ings led to the diagnosis of renal carcinoma at an early age. This exp erience suggests that children with tuberous sclerosis may need earlie r screening. (C) 1996 by W.B. Saunders Company