Jm. Thomason et al., THE DISTRIBUTION OF GINGIVAL OVERGROWTH IN ORGAN TRANSPLANT PATIENTS, Journal of clinical periodontology, 23(4), 1996, pp. 367-371
The distribution of gingival overgrowth was investigated in a cohort o
f organ transplant patients, who were medicated with cyclosporin or th
e combination of cyclosporin and a calcium channel blocking drug. Ging
ival overgrowth scores were significantly higher at buccal sites than
lingual-palatally (p<0.0001). There was no significant difference betw
een upper and lower overgrowth Cores (p=0.88). The most severe overgro
wth was seen in the canine region. Overgrowth between the central 0inc
isors was significantly less than in the canine region (p greater than
or equal to 0.044) and was similar to that in the molar and premolar
region. Although raised overgrowth scores were associated with increas
ed levels of plaque and gingival inflammation, the distribution could
not be explained by this observation.