Y. Qu et N. Farrell, ASSOCIATION OF MONONUCLEAR AND DINUCLEAR PLATINUM TETRAAMINE CATIONS WITH NUCLEOTIDES STUDIED BY N-15 NMR RELAXATION, Inorganica Chimica Acta, 245(2), 1996, pp. 265-267
By incorporation of labelled (NH3)-N-15 into the complex, the utility
of N-15 relaxation rates (T-1) in examining the association of mononuc
lear [Pt(NH3)(4)](2+) and dinuclear [{Pt(NH3)(3)}2NH2(CH2)(n)NH2](4+)
platinum-tetraamine cations with the mononucleotide 5'-GMP (guanosine-
5'-monophosphate) is demonstrated. No major differences between the mo
nonuclear and dinuclear complexes are seen.