A CASE OF RENAL-CELL CARCINOMA PRODUCING GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR

Authors
KAN M TAMURA M KOJIMA K NARUO S KANAYAMA HO KAGAWA S
Citation
M. Kan et al., A CASE OF RENAL-CELL CARCINOMA PRODUCING GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR, The Journal of urology, 155(6), 1996, pp. 2022-2023
Citations number
1
Categorie Soggetti
Urology & Nephrology
Journal title
The Journal of urology → ACNP
ISSN journal
00225347
Volume
155
Issue
6
Year of publication
1996
Pages
2022 - 2023
Database
ISI
SICI code
0022-5347(1996)155:6<2022:ACORCP>2.0.ZU;2-1
Abstract
Renal cell carcinomas frequently secrete hormones and cytokines (parat hormone, prostaglandins, renin, gonadotropins and glucocorticoids). Th e underlying cause of the leukemoid reaction sometime seen in renal ce ll carcinoma is unknown. We report a case of renal cell carcinoma with leukemoid reaction and demonstrate that the autonomous production of granulocyte-macrophage colony-stimulating factor in cancer tissue was the underlying mechanism.