J. Klekamp et al., ESTABLISHMENT OF A FREE CEREBROSPINAL-FLU ID PASSAGE FOR THE SURGICAL-TREATMENT OF SYRINGOMYELIA, Aktuelle Neurologie, 23(2), 1996, pp. 68-74
In a cooperative study between the Departments of Neurosurgery at the
University of California in Los Angeles, USA, and the Nordstadt Hospit
al in Hannover, Germany, the clinical course of 171 patients with syri
ngomeylia was documented retrospectively and prospectively. They under
went a total of 206 surgical procedures. Excluded from analysis were p
atients with syringomyelia due to tumours of the spinal canal. Only pa
tients with a progressive clinical course were operated on. Every pati
ent with syringomyelia demonstrated some form of cerebrospinal fluid f
low disturbance adjacent to the syrinx. Analysis of surgical results r
evealed that syrinx shunting procedures provided only temporary improv
ement or stabilization of symptoms. On a long-term basis shunting proc
edures were successful in only a few cases. Significantly better resul
ts were obtained with procedures intended to establish a free passage
of cerebrospinal fluid flow throughout the spinal canal. These observa
tions led to a pathophysiological hypothesis for the development of sy
ringomyelia and to a new concept for the surgical treatment of this di
sorder.