Rhinoscleroma is a rare, chronic granulomatous disease of infective ca
usation. It usually begins in the nose and may progress to involve the
larynx and trachea and cause dysphonia, strider, and airway obstructi
on. Early rhinoscleroma is usually successfully treated with oral tetr
acycline, yet laryngotracheal disease may require operative interventi
on. The disease is rare in the United States, but with an increase in
immigration from endemic areas, otolaryngologists should be familiar w
ith the management of this rare disease. Current literature contains o
nly a few reports describing the manifestations of this disease, mostl
y in the form of case studies. This study is a retrospective review of
our institutional experience with the management of 22 patients with
rhinoscleroma, 13 of whom had laryngotracheal involvement. The focus o
f this report is on the clinical manifestations of laryngotracheal scl
eroma. All of the patients were treated with long-term antibiotics. Ni
ne patients underwent endoscopy with or without dilation and laser exc
ision. Three patients required emergency tracheostomy, all of whom wer
e ultimately decannulated without any sequelae. A rational approach to
management of this unusual disease is provided.