PROGNOSTIC FACTORS IN SQUAMOUS-CELL CANCER OF THE VULVA AND THE IMPLICATIONS FOR TREATMENT

Authors
VANDERVELDEN J HACKER NF
Citation
J. Vandervelden et Nf. Hacker, PROGNOSTIC FACTORS IN SQUAMOUS-CELL CANCER OF THE VULVA AND THE IMPLICATIONS FOR TREATMENT, Current opinion in obstetrics & gynecology, 8(1), 1996, pp. 3-7
Citations number
36
Categorie Soggetti
Obsetric & Gynecology
Journal title
Current opinion in obstetrics & gynecology → ACNP
ISSN journal
1040872X
Volume
8
Issue
1
Year of publication
1996
Pages
3 - 7
Database
ISI
SICI code
1040-872X(1996)8:1<3:PFISCO>2.0.ZU;2-G
Abstract
Basic research in vulvar cancer results in new prognostic variables su ch as human papillomavirus DNA and epidermal growth factor receptor le vel. It also suggests that p53 mutants are involved in the pathogenesi s of this disease. However, histopathological parameters of the lymph nodes, such as capsule breakthrough are the most significant prognosti cators for patient survival.